human granulosa cell tumor cell line kgn  (Procell Inc)

Journal: Biomedicines

Article Title: Peritoneal Endometriosis Impairs Ovarian Reserve and Increases Atresia in a Rat Model

doi: 10.3390/biomedicines13020348

Figure Lengend Snippet: Effect of endometriotic cells on the expression of folliculogenesis-related genes in granulosa cells in vitro. The AMH ( A ), AMHR2 ( B ), KITLG ( C ), and MTOR ( D ) mRNA expressions were assessed in KGN granulosa cells by RT-qPCR. KGN cells were cultured alone (KGN) or co-cultured with 12Z endometriotic cells (KGN + 12Z) for 48 h. 18S or RPLP0 were used as housekeeping genes. Results are expressed as means ± SEM. n is expressed in parentheses in each bar. Statistical comparisons were performed by Student’s “ t ” test. * p < 0.05 KGN vs. KGN + 12Z.

Article Snippet: In this study, we used the immortalized human epithelial-like endometriotic cell line 12Z [ ] and the human granulosa tumor cell line KGN (RIKEN Bioresource Centre, Tsukuba, Japan).

Techniques: Expressing, In Vitro, Quantitative RT-PCR, Cell Culture

Journal: BMC Cancer

Article Title: A quinoline-2-thione derivative as a novel chemotherapy drug candidate displays anti-tumor activity in vitro and in vivo

doi: 10.1186/s12885-024-13042-7

Figure Lengend Snippet: KA3D had no effect on KGN ovarian granulosa cells

Article Snippet: The human granulosa cell line KGN (fibroblast-like granulosa cell tumor) was obtained from Procell Co., Ltd. (Wuhan, China).

Techniques: